cas 65705-83-1, (4R)-(3-[(3R,S)-3-CYCLOHEXYL-3-HYDROXYPROPYL]-2,5-DIOXO)-4-IMIDAZOLIDINE-HEPTANOIC ACID | Articles data ｜lookchem

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65705-83-1

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Heterocyclic Prostaglandin Analogues. Part 3. The Relationship of Configuration to Biological Activity for Some Hydantoin Prostanglandin Analogues
The enantiomers of the two diastereomers of 5-(6-carboxyhexyl)-1-(3-cyclohexyl-3-hydroxypropyl)hydantoin have been synthesised.Potent inhibition of platelet aggregation in this series is associated with the configuration corresponding to that in the natural inhibitors, such as prostaglandins E1 and D2.
Brockwell, Michael A.,Caldwell, A. Gordon,Whittaker, Norman,Begley, Michael J.
p. 706 - 711
(2007/10/02)

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More Articles about downstream products of 65705-83-1

73490-09-2
(+/-)-3-(3-cyclohexyl-3-oxopropyl)-2,5-dioxo-4-imidazolidineheptanoic acid

Chemical Properties

Solubility:≤50mg/ml in ethanol;50mg/ml in DMSO;50mg/ml in dimethyl formamide
PSA: 106.94000
LogP: 2.93000

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