Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3- aminopyridin-2(1H)-one
In an ongoing effort to develop novel nonnucleoside, specific human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) inhibitors, a series of 3-[(pyridylmethyl)amino]- and 3-[(phenylmethyl)amino]-2- pyridinone derivatives was synthesized an
Hydroxylated inhibitors of HIV reverse transcriptase
Novel biotransformed or synthetic hydroxy pyridinones inhibit HIV reverse transcriptase, and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts (where appropriate
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(2008/06/13)
Research about antibacterial activity of quinolone carboxylic acids. IX. Azaanologs. Di- and trisubstituted 1,4-dihydro-4- oxo-1,3-naphthyridine-3 carboxylic acids and 1-ethyl-4- pyridone-3 carboxylic acids
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Heindl,Kelm,Dogs,et al.
p. 549 - 555
(2007/10/08)
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