cas 691877-03-9, 3-Bromo-5-cyanobenzotrifluoride

Provided are fused tricyclic amide compounds, pharmaceutical compositions comprising at least one such fused tricyclic compound, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain tricyclic amide compounds that can be useful for inhibiting multiple (specifically BRAF and/or EGFR-T790M) kinases and for treating disorders mediated thereby.

The present invention is directed to compounds of the formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R11, R12, W, X, and n are defined herein, which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.

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Dayang Chem (Hangzhou) Co.,Ltd.
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Chemwill Asia Co., Ltd.
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Hebei Nengqian Chemical Import and Export Co., LTD
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Henan Tianfu Chemical Co., Ltd.
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Shanghai Upbio Tech Co.,Ltd
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Siwei Development Group Ltd.
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Shanghai Minstar Chemical Co., Ltd
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Golden Pharma Co., Limited
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691877-03-9

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Chemical Properties

Boiling Point: 216.039 °C at 760 mmHg

Flash Point:84.458 °C

Density: 1.719 g/cm³

Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly)

Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature

Vapor Pressure: 0.143mmHg at 25°C

Refractive Index: 1.517

PSA: 23.79000

LogP: 3.33958

Global suppliers and manufacturers of 691877-03-9total 52 suppliers on LookChem

Article Database

691877-03-9

Articles about 691877-03-9Total 2 be found

More Articles about upstream products of 691877-03-9

More Articles about downstream products of 691877-03-9

Chemical Properties

Boiling Point: 216.039 °C at 760 mmHg

Flash Point:84.458 °C

Density: 1.719 g/cm3

Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly)

Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature

Vapor Pressure: 0.143mmHg at 25°C

Refractive Index: 1.517

PSA: 23.79000

LogP: 3.33958

Global suppliers and manufacturers of 691877-03-9total 52 suppliers on LookChem

Density: 1.719 g/cm³