- Acyl acid derivative and preparation method and medical application thereof
-
The invention relates to an acyl acid derivative as well as a preparation method and medical application thereof. Specifically, the invention relates to a compound represented by a general formula (I), a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing the same, and the invention also relates to a use thereof as an active ingredient in the prevention and/or treatment of muscle atrophy-related diseases, including myogenic muscle atrophy, disuse muscle atrophy, senile muscle atrophy, neurogenic muscle atrophy, and a use in the prevention and/or treatment of obesity, fatty liver, cardiovascular and cerebrovascular diseases, metabolic diseases, and anti-aging, wherein the definition of each group in the general formula (I) is the same as the definition in the specification.
- -
-
Paragraph 0443-0446
(2020/07/02)
-
- Evaluation of hadacidin analogues
-
Several derivatives of hadacidin have been developed and evaluated for activity against adenylosuccinate synthetase.
- Tibrewal, Nidhi,Elliott, Gregory I.
-
supporting information; experimental part
p. 517 - 519
(2011/02/25)
-