- Perovskite as Recyclable Photocatalyst for Annulation Reaction of N-Sulfonyl Ketimines
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A sustainable and cost-effective manner for the photocatalytic annulation reaction of N-sulfonyl ketimines with N-arylglycines to synthesize imidazolidine-fused sulfamidates (31 examples) by employing CsPbBr3 as a heterogeneous photocatalyst has been developed. The catalyst CsPbBr3 can be simply recovered from the reaction mixture and reused at least five times without an obvious reduction in its photocatalytic reactivity, exhibiting a high catalyst economic feature.
- Shi, Anzai,Sun, Kai,Chen, Xiaolan,Qu, Lingbo,Zhao, Yufen,Yu, Bing
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supporting information
p. 299 - 303
(2022/01/04)
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- Photoredox-Catalyzed α-Aminomethyl Carboxylation of Styrenes with Sodium Glycinates: Synthesis of γ-Amino Acids and γ-Lactams
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A visible-light photoredox-catalyzed reductive α-aminomethyl carboxylation of styrenes with sodium glycinates and CO2 has been developed to synthesize a series of α,α-disubstituted γ-amino acids and γ-lactams with high efficiency and regioselectivity. Notably, CO2 released from the decarboxylation step can be reused for the subsequent carboxylation. Distinct from the previous reactions with the same type of substrates leading to simple decarboxylation and olefin hydroalkylation, this process involves additional CO2 sequestration, thus leading to olefin α-aminomethyl carboxylation. These findings not only provide new access to α,α-disubstituted γ-amino acids and γ-lactams but also serve as a proof of concept for CO2 reutilization in decarboxylation reactions.
- Zhou, Cong,Li, Miao,Sun, Jianwei,Cheng, Jiang,Sun, Song
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supporting information
p. 2895 - 2899
(2021/05/05)
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- Synthesis, antiproliferative, and antioxidant activities of substituted n-[(1,3,4-oxadiazol-2-yl) methyl] benzamines
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Background: Oxadiazole emerged as an important class of heterocyclic compound with diverse biological activities like anticancer, antitubercular, anticonvulsant, anti-tubulin, antimicrobial, anti-inflammatory, antioxidant etc. Objective: The objective of
- Ahsan, Mohamed Jawed,Bakht, Mohamed Afroz,Balaraju, Tuniki,Bhandari, Lakshya,Geesi, Mohammed H.,Gorantla, Vasubabu,Hassan, Mohd. Zaheen,Hussain, Afzal,Jadav, Surender Singh,Khalilullah, Habibullah,Makkar, Shally,Rani, Sandhya,Riadi, Yassine,Singh, Rajan
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p. 145 - 154
(2020/02/29)
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- FERROCHELATASE INHIBITORS AND METHODS OF USE
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The invention relates to a method of treatment of a patient with a ferrochelatase inhibitor, or a pharmaceutically acceptable salt thereof, or a derivative thereof. Also, the invention relates to a method of treatment of a patient with a ferrochelatase in
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Page/Page column 57
(2019/11/19)
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- Functionalization of N-arylglycine esters: Electrocatalytic access to C-C bonds mediated by n-Bu4NI
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An efficient electrocatalytic functionalization of N-arylglycine esters is reported. The protocol proceeds in an undivided cell under constant current conditions employing the simple, cheap and readily available n-Bu4NI as the mediator. In addition, it is demonstrated that the mediated process is superior to the direct electrochemical functionalization.
- Luo, Mi-Hai,Jiang, Yang-Ye,Xu, Kun,Liu, Yong-Guo,Sun, Bao-Guo,Zeng, Cheng-Chu
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supporting information
p. 499 - 505
(2018/03/21)
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- Copper Triflate Catalyzed Oxidative α-Allylation of Glycine Derivatives
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Copper triflate catalyzed oxidative C-H functionalization of glycine derivatives with allyltributyltin has been established using oxygen or tert -butyl hydroperoxide as oxidant. Various glycine esters and glycine amides were suitable substrates for this oxidative allylation reaction and afforded the desired homoallylic amines in moderate to good yields.
- Chen, Ting-Ting,Cai, Chun
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supporting information
p. 1368 - 1372
(2017/06/27)
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- MYOGLOBIN-BASED CATALYSTS FOR CARBENE TRANSFER REACTIONS
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Methods are provided for carrying out carbene transfer transformations such as olefin cyclopropanation reactions, carbene heteroatom-H insertion reactions (heteroatom = N, S, Si), sigmatropic rearrangement reactions, and aldehyde olefination reactions with high efficiency and selectivity by using a novel class of myoglobin-based biocatalysts. These methods are useful for the synthesis of a variety of organic compounds which contain one or more new carbon-carbon or carbon-heteroatom (N, S, or Si) bond. The methods can be applied for conducting these transformations in vitro (i.e., using the biocatalyst in isolated form) and in vivo (i.e., using the biocatalyst in a whole cell system).
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Paragraph 0071; 00266
(2016/06/14)
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- Iron-catalyzed direct α-arylation of α-amino carbonyl compounds with indoles
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A mild and general α-arylation of α-amino carbonyls with indoles catalyzed by Fe(ClO4)3 has been developed. C-H activation is smoothly fulfilled by using TBHP as the oxidant with good yields. Two hydrogen dissociations make this transformation more environmentally benign because of high atom efficiency.
- Zhang, Yan,Ni, Minjie,Feng, Bainian
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supporting information
p. 1550 - 1554
(2016/02/10)
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- Myoglobin-catalyzed intermolecular carbene N-H insertion with arylamine substrates
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Engineered variants of the heme-containing protein myoglobin can efficiently catalyze the insertion of α-diazo esters into the N-H bond of arylamines, featuring a combination of high chemoselectivity, elevated turnover numbers, and broad substrate scope.
- Sreenilayam, Gopeekrishnan,Fasan, Rudi
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p. 1532 - 1534
(2015/08/03)
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- Iron-catalyzed oxidative tandem reactions with TEMPO oxoammonium salts: Synthesis of dihydroquinazolines and quinolines
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A straightforward iron-catalyzed divergent oxidative tandem synthesis of dihydroquinazolines and quinolines from N-alkylanilines using a TEMPO oxoammonium salt as a mild and nontoxic oxidant has been developed. Fe(OTf) 2 was the Lewis acid cata
- Rohlmann, Renate,Stopka, Tobias,Richter, Heinrich,Garcia Mancheno, Olga
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p. 6050 - 6064
(2013/07/26)
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- Microwave-assisted synthesis of N-arylglycines: Improvement of sydnone synthesis
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Reactions of anilines with ethyl bromoacetate under microwave irradiation have afforded N-arylglycines that are subsequently converted to their N-nitroso derivatives with a combination of silica chloride or periodic acid, wet SiO2 and sodium nitrite in CH2Cl2 with satisfactory yields. In the final step, the use of 1,3-dibromo-5,5-dimethylhydantoin (DBH) as a new and effective reagent for dehydration of N-nitroso-N-arylglycines to sydnones was successfully examined.
- Azarifar, Davood,Bosra, Hassan Ghasemnejad,Zolfigol, Mohammad-Ali,Tajbaksh, Mahmood
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p. 175 - 181
(2007/10/03)
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