- Basic thioethers
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Basic thioethers of the formula wherein R is p-R5 -S-phenyl or 2-dibenzothienyl; A is --CHR3 --CHR4 --, --CR3 (OH)--CHR4 --, --CHR3 --CR4 (OH)-- or --CR3 =CR4 --; Z is --NR1 R2, 1-imidazolyl or 1,2,4-triazol-1-yl; n is 1, 2 or 3; R1 and R2 are the same or different and each is H, alkyl of 1-4 carbon atoms or together form alkylene of 4-7 ring carbon atoms, or form 3-oxapentamethylene; R3 and R4 are the same or different and each is H, alkyl of 1-4 carbon atoms or phenyl; R5 is an unsubstituted phenyl or benzyl group or a phenyl or benzyl group substituted with 1 or 2 of halogen, nitro, amino and/or alkoxy of 1-4 carbon atoms, alkyl of 1-6 carbon atoms, or cycloalkyl of 3-7 ring carbon atoms, with the proviso that R5 is alkyl of 1-6 carbon atoms, or cycloalkyl of 3-7 ring carbon atoms when A is --CHR3 --CH2 -- and Z is 1-imidazolyl possess valuable pharmacological properties.
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