Double duty for cyanogen bromide in a cascade synthesis of cyanoepoxides
An unprecedented reaction mode of cyanogen bromide has been discovered. Under basic conditions, cyanogen bromide acts as an equivalent of both Br + and CN- to convert enolizable ketones into the corresponding cyanoepoxides in good yields. This unique reaction mode provides new, one-pot access to densely substituted cyanoepoxides from easily available ketones (see scheme). Copyright
Li, Zhou,Gevorgyan, Vladimir
supporting information; experimental part
p. 2808 - 2810
(2011/05/05)
More Articles about upstream products of 7136-23-4