- FUNCTIONALISED AND SUBSTITUTED CARBAZOLES AS ANTI-CANCER AGENTS
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The present invention relates to anti-tropomyosin compounds, processes for their preparation, and methods for treating or preventing a disease or disorder, such as a proliferative disease (preferably cancer), using compounds of the invention.
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Page/Page column 38; 39
(2016/02/26)
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- N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors
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Small molecule inhibitors of adipocyte fatty-acid binding protein (A-FABP) have gained renewed interest following the recent publication of pharmacologically beneficial effects of such inhibitors. Despite the potential utility of selective A-FABP inhibito
- Barf, Tjeerd,Lehmann, Fredrik,Hammer, Kristin,Haile, Saba,Axen, Eva,Medina, Carmen,Uppenberg, Jonas,Svensson, Stefan,Rondahl, Lena,Lundbaeck, Thomas
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scheme or table
p. 1745 - 1748
(2010/02/28)
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- ACYLGUANIDINE DERIVATIVE
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An object of the present invention is to provide a novel and excellent agent for treating or preventing dementia, schizophrenia and the like, based on the 5-HT5A receptor modulating action. It was confirmed that a compound characterized by a st
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Page/Page column 17
(2009/12/05)
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- ACYLGUANIDINE DERIVATIVE OR SALT THEREOF
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[Problem] To provide a compound which can be used in the prevention and/or treatment of diseases in which S-HT2B receptor and 5-HT7 receptor are concerned, particularly in the treatment of irritable bowel syndrome (IBS) and/or preven
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Page/Page column 20
(2008/12/05)
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- NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS
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The present invention relates to novel compounds (I) wherein R0, R1, R2, R3, R4, R5, R6, R7, R8, A, B, n, X, and Y are as defined in the description and claims; and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament, which acts on the fatty acid binding protein FABP-4. The present invention relates to novel compounds (I) wherein R0, R1, R2, R3, R4, R5, R6, R7, R8, A, B, n, X, and Y are as defined in the description and claims; and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament, which acts on the fatty acid binding protein FABP-4.
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