Chiral, non-racemic α-hydroxyphosphonates and phosphonic acids via stereoselective hydroxylation of diallyl benzylphosphonates
Chiral, non-racemic α-hydroxyphosphonates have been prepared in high enantiomeric excess (96-98% ee), via stereoselective oxaziridine-mediated hydroxylation of diallyl benzylphosphonates. The enantiomeric purity and absolute configuration of the α-hydroxy
Skropeta, Danielle,Schmidt, Richard R.
p. 265 - 273
(2007/10/03)
SAR directed design and synthesis of novel β(1-4)-glucosyltransferase inhibitors and their in vitro inhibition studies
This paper describes SAR directed design and synthesis of novel β (1-4)-glucosyltransferase (BGT) inhibitors. The designed inhibitors 1 5 provide conformational mimicry of the transition-state in glucosyltransfer reactions. The compounds were tested for i
Bhattacharya, Asish K,Stolz, Florian,Kurzeck, Juergen,Rueger, Wolfgang,Schmidt, Richard R
p. 1129 - 1136
(2007/10/03)
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