- Precise Steric Control over 2D versus 3D Self-Assembly of Antimony(III) Alkoxide Cages through Strong Secondary Bonding Interactions
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Antimony(III) alkoxide cages were designed as building blocks for predictable supramolecular self-assembly. Supramolecular synthons featuring two Sb···O secondary bonding interactions (SBIs), each SBI stronger than 30 kJ/mol, were used to drive the formation of the supramolecular architectures. Judicious choice of pendant groups provided predictable control over the formation of self-assembled 3D columnar helices, which crystallized with hollow morphologies, or a self-assembled 2D bilayer. The Sb-O stretching frequency provides a spectroscopic signature of Sb···O SBI formation.
- Moaven, Shiva,Yu, Jingze,Yasin, Jason,Unruh, Daniel K.,Cozzolino, Anthony F.
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- SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF
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A compound is shown in formula (I). The derivatives of the compound include a stereoisomer, a pharmaceutically acceptable salt, a solvate, a prodrug, a metabolite, a deuterated derivative. The compound is a structurally novel substituted imidazole formate derivative. Substituted imidazole formate derivatives are used in preparing a drug with sedative, hypnotic and/or anesthetic effects, as well as a drug that can control the state of epilepsy. The compound has a good inhibitory effect on the central nervous system, and provides a new option for clinical screening of and/or preparation of a drug with sedative, hypnotic and/or anesthetic effects and controlling the state of epilepsy.
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Paragraph 0541-0543
(2020/12/08)
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- ORTHO ESTER DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT
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The invention is to provide a liquid crystal compound having a large dielectric anisotropy, a high voltage holding ratio and stability to heat, light and so forth, maintaining a nematic phase in a wide temperature range, having a suitable optical anisotropy and an excellent compatibility with other liquid crystal compounds, particularly, to provide a liquid crystal compound having a large dielectric anisotropy. The invention provides compound (1): In the formula, for example, R1 is alkyl and having 1 to 20 carbons; ring A1, ring A2, ring A3, ring A4, ring A5 and ring A6 are independently 1,4-cyclohexylene or 1,4-phenylene; Z1, Z2, Z3, Z4, Z5, Z6 and Z7 are independently a single bond, - (CH2) 2-, -COO-, -OCO-, CF2O-, -OCF2- or -CH=CH-; X1 is fluorine, -CF3 or -OCF3; and Y1 and Y2 are independently hydrogen or fluorine.
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Paragraph 0147
(2014/02/15)
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- Pesticidal compounds
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The present invention provides a class of novel substituted bicyclooctanes which have pesticidal activity, particularly against arthropod pests. Pesticidal formulations containing the compounds of the formula (I), their use in the control of pests and methods for their preparation are also disclosed.
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- Pesticidal compounds
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Bicyclooctane pesticides of the formula are prepared by cyclisation of In these formulae R may be various organic groups and is preferably n-butyl or n-propyl while R2 is a polysubstituted phenyl group.
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- Improvements relating to pesticides
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Bicyclo-octane pesticides have the formula where Z is CH2CH2, CH2O, CH2S, -COCH2 or CH(OR8)CH2 where R8 is H, alkyl, acyl or carbamoyl; Y and Y1 are O or S(O)mwhere m is 0, 1 or 2; R is a specified substituted or unsubstituted aliphatic or cycloaliphatic hydrocarbon groups or a phenyl group, R1 and R3 are H, or specified substituted or unsubstituted aliphatic hydrocarbon groups or R1 is a carboalkoxy, cyano or gem dimethyl group when R3 is H or R and R1, together with the carbon atoms to which they are attached form a carbocyclic ring; and R2 is a phenyl group substituted at position 4 by -(C≡C)nR5 and optionally at other positions by specified substituents where n is 1 or 2 and R5 is I, H, alkyl optionally substituted, carboalkoxy, or a trisubstituted tin or trisubstituted silicon group. Various methods of synthesis are given.
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- Base reactant
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Alkyl nitriles in combination with alkali metal hydroxides provide super bases which are useful in various chemical processes.
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