Practical synthesis of a vanilloid receptor-1 antagonist
(Chemical Equation Presented) Small molecule TRPV1 antagonists have been a recent focus in the search for pain treatment agents. We herein describe a practical and scalable synthesis of AMG 628 (1), a bis-substituted pyrimidine derivative that was identif
Thiel, Oliver R.,Bernard, Charles,King, Tony,Dilmeghani-Seran, Mina,Bostick, Tracy,Larsen, Robert D.,Faul, Margaret M.
p. 3508 - 3515
(2008/09/21)
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