cas 74842-55-0, BENZYL N-ACETYL-4,6-O-BENZYLIDENEMURAMIC ACID | Articles data ｜lookchem

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74842-55-0

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Optimization of UDP-N-acetylmuramic acid synthesis
UDP-N-acetylmuramic acid (UDP-MurNAc) is a substrate of MurC, an important enzyme in the intracellular pathway of bacterial peptidoglycan biosynthesis. Various approaches towards preparation of UDP-Mur/VAc have been published but these synthetic preparations were shown to include many problematic steps. An optimization study with the focus on muramyl phosphate and UMP-morpholidate coupling was performed, resulting in a synthetic procedure enabling robust and easily reproducible production on a multi-gram scale.
Humljan, Jan,Starcevic,Car,Stefanic Anderluh,Kocjan,Jenko,Urleb
p. 102 - 106
(2008/09/21)

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Chemical Properties

Appearance/Colour :white crystalline solid
Melting Point: 237-239 °C
Boiling Point: 717.7 °C at 760 mmHg
Flash Point:387.8 °C
Density: 1.31 g/cm³
Storage Temp.:2-8°C
Vapor Pressure: 1.29E-21mmHg at 25°C
Refractive Index: 1.595

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