COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
The present invention is directed to therapeutic compounds which have dual activity as agonists of GPR119 and inhibitors of DPP-IV and are useful for the treatment of metabolic disorders including type II diabetes.
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(2009/04/25)
Synthesis and microbiological activities of some monohalogenated analogs of tyrosine
2 Chlorotyrosine and 2 bromotyrosine, as well as the previously reported 2 fluorotyrosine, were synthesized by hydrolysis of the condensation products from the appropriate benzyl bromide and ethyl acetamidomalonate and were compared with the corresponding