Synthesis of analogues of acetylmethadol and methadol as potential narcotic antagonists
The N-allyl and N-(cyclopropylmethyl) analogues of (-)-α-acetylmethadol and (-)-α-methadol have been synthesized and evaluated for opiate agonist and opiate antagonist activity. Both acetylmethadol analogues possessed weak analgesic activity in in vivo te
Lattin,Caviness,Hudson,Greene,Raible,Richardson
p. 903 - 906
(2007/10/02)
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