- Synthesis of Optically Active α-Methylene β-Lactams through Lipase-Catalyzed Kinetic Resolution
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A convenient method for the preparation of the hitherto unknown chiral α-methylene β-lactam derivatives 5a,b is reported. The optically active α-methylene β-lactams 5a-c, and their corresponding amino acids 6a-c have been readily made available through li
- Adam, Waldemar,Groer, Peter,Humpf, Hans-Ulrich,Saha-Moeller, Chantu R.
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p. 4919 - 4922
(2007/10/03)
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- Synthesis of 3-Methyleneazetidin-2-one Derivatives from α-Keto-amides
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Several α-methyleneazetidin-2-one derivatives (CH2=CCONR1CHR2, R1 = cyclohexyl, PhCH2; R2 = H, Me, Et, Prn, etc.) were prepared from the 2-(2,4,6-tri-isopropylbenzenesulphonylhydrazones) of primary α-
- Adlington, Robert M.,Barrett, Anthony G.M.,Quayle, Peter,Walker, Andrew,Betts, Michael J.
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p. 605 - 612
(2007/10/02)
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- Novel Syntheses of 3-Methylene-azetidin-2-one Derivatives and Related Systems
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Syntheses of the title compounds via 1-lithio-oxy-1-lithio-amino-allene derivatives or lithium phenylethynolate are described.
- Adlington, Robert M.,Barrett, Anthony G. M.,Quayle, Peter,Walker, Andrew,Betts, Michael J.
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p. 404 - 405
(2007/10/02)
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