Axial chiral allenylacetates as novel ferroelectric liquid crystals
Liquid crystalline alkane-3,4-dienoates (allenylacetates) have been synthesized. Most compounds incorporate a heterocyclic 1,3,4-thiadiazole ring or a pyrimidine ring as a constituent of the rigid core. These axial chiral allene derivatives were at first
Lunkwitz, Ralph,Tschierske, Carsten,Langhoff, Arne,Giesselmann, Frank,Zugenmaier, Peter
p. 1713 - 1721
(2007/10/03)
A NOVEL FIVE-CARBON HOMOLOGATION LEADING TO 3,4-ALKADIENOIC ACIDS BY SN2' REACTION OF β-ETHYNYL-β-PROPIOLACTONE WITH GRIGNARD REAGENTS IN THE PRESENCE OF COPPER(I) CATALYST
β-Ethynyl-β-propiolactone reacts regioselectively with Grignard reagents in the presence of copper(I) catalyst to afford 3,4-alkadienoic acids in high yields.Synthetic utility of this reaction is demonstrated in the simple synthesis of pellitorine.