Studies in Antifertility Agents : Part XXXVI-Syntheses of N-(Substituted benzylidene)amino-phthalimides, -dihydroisoindoles and -1,2,3,4-tetrahydroisoquinolines
Syntheses and antifertility activity of a number of N-(substituted benzylidene)amino-phthalimides (3a-i), -dihydroisoindoles (4a-i) and -1,2,3,4-tetrahydroisoquinolines (5a-i) are reported.Some of these compounds prevent pregnancy when administered at 25 mg/kg/day in mice. 100percent abortifacient actvity has been shown by some of these compounds in rats at 20 mg/kg.
Salman, Mohammad,Ray, Suprabhat
p. 477 - 479
(2007/10/02)
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