- Quinazolinone Compound and Application Thereof
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The present invention relates to a series of quinazolinone compounds and applications thereof as PI3Kα inhibitors. In particular, the present invention relates to a compound shown in formula (I) and a tautomer or pharmaceutically acceptable salt thereof.
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Paragraph 0118-0120; 0140-0142; 0127-0129
(2020/11/27)
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- PYRAZOLE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS
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The invention concerns pyrazole derivatives of Formula( I) or pharmaceutically-acceptable salts thereof, wherein each of R, Ring A, m, R1, R2 and R3 has any of the meanings defined hereinbefore in the description; processe
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Page/Page column 77
(2008/06/13)
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- INDOLE DERIVATIVES
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The invention concerns indole derivatives of Formula (I) or pharmaceutically-acceptable salts thereof, wherein each of Ring A, m, R1, R2, n, R3 and G1 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in therapy, for example in the treatment of disease mediated by a PI3K enzyme and/or a mTOR kinase.
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- Bispiperidines as antithrombotic agents
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Novel compounds which are inhibitors of the binding of fibrinogen to the Gp IIb/IIIa platelet receptors, and which can be used therepeutically as antithrombotic agents
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- Some Heterocyclic Sulfonyl Chlorides and Derivatives
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The syntheses of 4- and 5-chlorosulfonylfuran-2-carboxylic acid (Ia,IIa), 4-chlorosulfonylfuran-2-carboxamide (Ib), 3,5-dimethylpyrazole and isoxazole-4-sulfonyl chlorides (IIa, IVa) and 2,4-dimethylthiazole-5-sulfonyl chloride (Va) are described.The sulf
- Cremlyn, Richard J.,Swinbourne, Fred J.,Yung, Kin-Man
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p. 997 - 1006
(2007/10/02)
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