Chemistry of 5(2H)-Isoxazolones: Novel Conversion of Positional Isomers
Reactions of 4-arylidene-3-methyl-5(4H)-isoxazolones with nucleophiles lead to 4-substituted-benzyl-3-methyl-5(2H)-isoxazolones.Formation of 5(4H)- and 5(2H)-isoxazolone derivatives have been observed when 4-substituted-arylidene-3-methyl-5(4H)-isoxazolon
Batra, Sanjay,Akhtar, Mohammed Shamim,Seth, Manju,Bhaduri, Amiya Prasad
p. 337 - 342
(2007/10/02)
OXIDATION OF 3,4-DISUBSTITUTED ISOXAZOLIN-5-ONES. A NEW SYNTHESIS OF α-KETO ACIDS
m-Chloroperoxybenzoic or peroxyformic acid oxidation of 3,4-disubstituted isoxazolin-5-ones affords the corresponding 4-hydroxy derivatives from which, by ring opening, nitriles and α-keto acids are obtained.