Base-catalysed asymmetric hydroamination/cyclisation of aminoalkenes utilising a dimeric chiral diamidobinaphthyl dilithium salt
A dimeric proline derived diamidobinaphthyl dilithium salt represents the first example of a chiral main group metal based catalyst for asymmetric hydroamination/cyclisation reactions of aminoalkenes. The Royal Society of Chemistry 2006.
Martinez, Patricia Horrillo,Hultzsch, Kai C.,Hampel, Frank
p. 2221 - 2223
(2007/10/03)
Asymmetric Aldol Reaction between Achiral Silyl Enol Ethers and Achiral Aldehydes by Use of a Chiral Promoter System
In the presence of a chiral promoter consisting of tin(II) triflate, a chiral diamine, and tributyltin fluoride, the silyl enol ether of S-ethyl ethanethioate or S-tert-butyl ethanethioate reacts with aldehydes to afford the corresponding aldol-type adduc
THE ENANTIOFACE-DIFFERENTIATING METHYLATION OF THE N-BENZYLIDENE-DL-PHENYLALANINE METHYL ESTER IN THE PRESENCE OF CHIRAL LITHIUM AMIDES
The asymmetric methylation of the N-benzylidene-DL-phenylalanine methyl ester was carried out in the presence of lithium salts of secondary amines derived from (S)-proline.The lithium amides of poly-(imino-1-isobutylethylene) and its corresponding low-molecular-weight model compound, derived from (S)-leucine, were similarly used in order to examine the polymer effects with regard to the stereoselectivity.