- Perylenequinonoid-Catalyzed [4 + 1] and [4 + 2] Annulations of Azoalkenes: Photocatalytic Access to 1,2,3-Thiadiazole/1,4,5,6-Tetrahydropyridazine Derivatives
-
Nitrogen-containing heterocycles are especially considered "privileged" structural scaffolds for the development of new drugs. However, traditional methods of organic synthesis are mainly based on thermal cycloaddition reaction; thus, the exploration of n
- Zhang, Yan,Cao, Yuan,Lu, Liushen,Zhang, Shiwei,Bao, Wenhao,Huang, Shuping,Rao, Yijian
-
p. 7711 - 7721
(2019/06/17)
-
- Ionic liquid as soluble support for synthesis of 1,2,3-thiadiazoles and 1,2,3-selenadiazoles
-
A convenient synthesis of 1,2,3-thiadiazoles and 1,2,3-selenadiazoles was achieved using an ionic liquid as a novel soluble support. Ionic liquid-supported sulfonyl hydrazine was synthesized and reacted with a number of ketones to afford the corresponding ionic liquid-supported hydrazones that were converted to 1,2,3-thiadiazoles in the presence of thionyl chloride. The reaction of ionic liquid-supported hydrazones with selenium dioxide in acetonitrile afforded 1,2,3-selenadiazoles. The advantages of this methodology were the ease of workup, simple reaction conditions, and high purity.
- Kumar, Anil,Muthyala, Manoj Kumar,Choudhary, Sunita,Tiwari, Rakesh K.,Parang, Keykavous
-
p. 9391 - 9396,6
(2012/12/11)
-
- Synthesis of 1,2,3-Thiadiazole-5-carbaldehydes and their Conversion into 6aλ4-Thia-1,2,5,6-tetraazapentalenes
-
A convenient method for the synthesis of the virtually unknown 1,2,3-thiadiazole-5-carbaldehydes consists in monobromination of the 5-methyl derivatives, followed by treatment with sodium azide and decomposition in concentrated sulfuric acid (6 -> 7 -> 9
- L'abbe, Gerrit,Frederix, Ann
-
p. 1415 - 1418
(2007/10/02)
-
- Kinetics and Mechanism of the Reaction of Thionyl Chloride with Substituted Acetophenone Semicarbazones. The Synthesis of 1,2,3-Thiadiazoles
-
The reaction of thionyl chloride with a series of para-substituted acetophenone semicarbazones, which gives 1,2,3-thiadiazoles, involved an electrophilic attack.The rates correlated with the substituent ?+ constants and gave a Hammett ρ value o
- Butler, Richard N.,O'Donoghue, Denis A.
-
p. 1223 - 1228
(2007/10/02)
-