- NOVEL HETEROARYL-AMINO DERIVATIVES
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Disclosed is a compound of formula (I), wherein R1, R2, L, Rm and Rn are as defined herein. The compound of formula (I) may be used in preventing and/or treating acyl CoA-diacylglycerol acyltransferase 1(DGAT-1) related diseases, such as obesity, coronary disease, hypertension, hyperlipidemia, arteriosclerosis, type II diabetes, stroke, hepatitis C, and the like.
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Page/Page column 29; 44; 45
(2013/05/09)
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- DDQ-promoted C-S bond formation: Synthesis of 2-aminobenzothiazole derivatives under transition-metal-, ligand-, and base-free conditions
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A transition-metal-free method for the intramolecular S-arylation of o-halobenzothiaoureas via DDQ-mediated leading to the 2-aminobenzothiazole derivatives is reported. The reactions are performed at room temperature under ligand- and base-free conditions with good to excellent yields. Georg Thieme Verlag Stuttgart · New York.
- Wang, Rui,Yang, Wen-Juan,Yue, Liang,Pan, Wei,Zeng, Hong-Yao
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experimental part
p. 1643 - 1648
(2012/08/07)
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- Direct transition metal-free C-S bond formation: Synthesis of 2-aminobenzothiazole derivatives via base-mediated approach
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A general, efficient, and more practical protocol for the base-mediated intermolecular or intramolecular S-arylation leading to the 2-aminobenzothiazole derivatives is reported. Remarkably, all reactions were carried out under transition-metal-free conditions with good to excellent yields, rendering the methodology presented herein highly valuable from both environmental and economic points of view.
- Wang, Rui,Chen, Zhi,Yue, Liang,Pan, Wei,Zhao, Jun-Jie
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experimental part
p. 4529 - 4531
(2012/09/22)
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