First asymmetric enantioselective total synthesis of phenanthridine alkaloid, (S)-(+)-asiaticumine and its enantiomer
In this study, the first asymmetric enantioselective total syntheses of (+)-asiaticumine A (2) and its enantiomer were accomplished through a seven-step sequence using the bond formation between the C4a and N5 positions of the phenanthridine framework bas
A highly efficient synthesis of trispheridine through a construction of tetrahydrophenanthridine based on a microwave-assisted thermal electrocyclic reaction of an aza 6π-electron system
A highly efficient synthesis of a phenanthridine alkaloid, trispheridine (1) has been achieved in a 74% overall yield in a four-step sequence. The key step is the construction of a tetrahydrophenanthridine based on a microwave-assisted thermal electrocycl