Conjugate addition of amides to α,β-unsaturated esters by CsF-Si(OEt)4 system
The conjugate addition of amides to α,β-unsaturated esters proceeds efficiently with an equimolar amount of Si(OEt)4 and a catalytic amount of CsF to afford the corresponding N-substituted amides.
Rhodium(II) acetate catalyzed synthesis of cyclic enamides and enamines via β-hydride elimination
A series of cylic diazoamides and diazoamines were synthesized. Treatment of these cylic diazoamides and diazoamines with a catalytic amount of rhodium(II) acetate furnished the corresponding cyclic enamides and enamines, respectively. Interestingly, cyclic diazoamines produced stereoselectively Z-enamines.