Provided herein are compounds, pharmaceutical compositions, and methods for binding or degrading target proteins. Further provided herein are compounds having a DNA damage-binding protein 1 (DDB1) binding moiety. Some such embodiments include a linker. Some such embodiments include a target protein binding moiety. Further provided herein are ligand-DDB1 complexes. Further provided herein are in vivo modified DDB1 proteins.
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(2021/12/08)
Synthesis method of 2-[3'-(N-Boc-pyrrolyl)]-benzoic acid
The invention belongs to the field of organic synthesis and discloses a synthesis method of 2-[3'-(N-Boc-pyrrolyl)]-benzoic acid. The synthesis method provided by the invention comprises the step of synthesizing the 2-[3'-(N-Boc-pyrrolyl)]-benzoic acid by
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(2019/12/25)
2-OXO-PIPERIDINYL DERIVATIVES
The present invention relates to 2-oxo-piperidinyl derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
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(2013/04/25)
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