- Halobenzene cyanopyrazole compound containing purine structure as well as preparation method and application
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The invention discloses a halobenzene cyanopyrazole compound containing a purine structure as well as a preparation method and an application. The halobenzene cyanopyrazole compound is a compound with a general structure (I) as shown in the specification or a pharmaceutically acceptable salt thereof. The compound is low in dosage, good in insecticidal efficacy, simple in technique, low in cost and wide in market prospect.
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Paragraph 0085
(2016/10/31)
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- Synthesis and spectroscopic characterization of some new biological active azo-pyrazoline derivatives
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A number of 3-[4-(benzyloxy)-3-(2-Chlorophenylazo)-phenyl]-5- (substituted-phenyl)-1- substituted-2-pyrazolines( 4a-j) and (5a-j) have been synthesized by diazotization of 2-chloroaniline and its coupling reaction with 4-hydroxy acetophenone, followed by benzyloxation of the hydroxyl group to give the substrate [4-benzyloxy-3-(2-chlorophenylazo)- acetophenone (1)].The prepared starting material (1) has been reacted with different substituted benzaldehydes to give a new series of chalcone derivatives 1-[(4- benzyloxy)-3-(2-chloro- phenylazo) -phenyl]-3- (substituted phenyl)-2-propen-1-one (3a-j) , in high yields and in a few minutes, and the later compounds were treated with hydrazine hydrate according to Michael addition reaction to afford a new biolological active target compounds (4a-j) and (5a-j). Furthermore, The structures of the newly synthesized compounds were confirmed by FT-IR, 13C-NMR, 13C-DEPT & 1H-NMR spectral data. The chalcone and pyrazoline derivatives were evaluated for their anti bacterial activity against Escherichia coli as gram negative and Staphylococcus aureus as gram positive, the results showed significant activity against both types of bacteria.
- Hawaiz, Farouq E.,Samad, Mohammad K.
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scheme or table
p. 1613 - 1622
(2012/06/01)
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- PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS.
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A pigment dispersion comprising a colour pigment and a polymeric dispersant having at least one pending chromophore group covalently bound to the polymeric backbone of the polymeric dispersant through a linking group wherein the at least one pending chromophore group is a derivative from a colour pigment selected from the group consisting of monoazo pigments, disazo pigments, β-naphtol pigments, naphtol AS pigments, azo pigment lakes, benzimidazolone pigments, disazo condensation pigments, metal complex pigments, isoindolinone pigments, isoindolinine pigments, phthalocyanine pigments, quinacridone pigments, diketopyrrolo-pyrrole pigments, thioindigo pigments, anthraquinone pigments, anthrapyrimidine pigments, indanthrone pigments, flavanthrone pigments, pyranthrone pigments, anthanthrone pigments, isoviolanthrone pigments, aluminium pigment lakes, dioxazine pigments, triarylcarbonium pigments and quinophthalone pigments; the at least one pending chromophore group is a chromophore group occurring as a side group on the polymeric backbone and not a group in the polymeric backbone itself or occurring solely as an end group of the polymeric backbone; the linking group consists of all the atoms between the polymeric backbone and the first atom of the aromatic group by which the pending chromophore group is linked to the polymeric backbone; the polymeric dispersant has a polymeric backbone with a polymerization degree between 5 and 1000; and at most 30 % of the monomer units of the polymeric backbone have a pending chromophore group. The pigment dispersion can be advantageously used in inkjet inks. Also disclosed is a method for preparing the pigment dispersion comprising the step of preparing the polymeric dispersant by copolymerizing a monomer already containing the pending chromophore group.
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Page/Page column 48-49
(2010/11/25)
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- Synthesis, characterization and antimicrobial studies of some novel 3- arylazo-7-hydroxy-4-methylcoumarins
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A series of 3-arylazo-7-hydroxy-4-methylcoumarins have been synthesized in excellent yields (80-90%) and their structures established on the basis of IR, 1H NMR, mass spectral data and elemental analyses. Their purity has been ascertained by ch
- Sharma, Pratibha,Pritmani, Shreeya
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p. 1139 - 1142
(2007/10/03)
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- Reaction of Triazene 1-Oxides: Novel Synthesis of Solid Arenediazonium Chlorides
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Treatment of 1,3-diaryltriazene 1-oxides with oxalyl chloride in dry toluene at room temperature gives only solid arenediazonium chlorides; however, treatment with acetyl and benzoyl chlorides does not afford the corresponding diazonium chlorides.
- Mohamed, Shaaban K.,Gomaa, Mohsen A.-M.,Nour El-Din, Ahmed M.
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p. 166 - 167
(2007/10/03)
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- The Influence of Chlorine and Sulphonate Substituents on the Visible Absorption Maxima of Some Azo Dyes
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A total of 110 arylazo dyes have been prepared, based on five benzenoid and heterocyclic coupling components, and containing combinations of chlorine and sulphonate (sulpho) substituents in the diazo components.Their visible absorption maxima have been analysed in order to determine the degree to which chloro and sulfo substituent influences are constant and transferable, both within a series, and between series.Additivity is found to pertain, if allowances are made for steric effects.A 2-sulpho group alone can induce nonplanarity, depending on the nature of the coupling component.The 2-sulpho-3-chloro combination is particularly responsible for hypsochromic shifts unexpected on the basis of strict additivity.Computer-aided molecular modelling studies have clarified the steric interactions present.Di-ortho-substitution also induces nonplanarity and hypsochromic effects.There is some evidence for non-equivalence of a substituent in the two distinct meta-orientations, although MO calculations do not reproduce this behaviour.
- Greenwood, David,Hutchings, Michael G.,Lamble, Brian
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p. 1107 - 1114
(2007/10/02)
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- Antiimplantation Agents: Part I - 1-Arylthiosemicarbazides
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Several 1-arylthiosemicarbazides, 2-arylhydrazinothiazolines and 2-arylhydrazinodihydrothiazines have been examined for their antiimplantation activity in rats.Among the active compounds, 4-methyl-1-(3,5-bistrifluoromethylphenyl)thiosemicarbazide (3, C 2696-Go) and the corresponding 4,4-dimethyl (47), ethyl (4), n-butyl (5) and allyl (6) derivatives completely inhibit implantation at doses 10, 3, 20, 20 and 30 mg/kg respectively.The 3,4-dichlorophenyl analogue (32) is effective at a dose of 30 mg/kg. 2-(3,5-Bistrifluoromethylphenyl)hydrazinothiazoline (51) and the corresponding dihydrothiazine (63) show a weaker activity.The biological profile of C 2696-Go has been investigated in detail.It appears to prevent implantation by its antiuterotropic activity and ability to inhibit desiduoma formation.
- Nagarajan, K.,Talwalker, P.K.,Kulkarni, C.L.,Venkateswarlu, A.,Prabhu, S.S.,Nayak, G.V.
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p. 1243 - 1257
(2007/10/02)
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