The reaction between chloroacetyl chloride and mono- or bis-aliphatic or aromatic amines in water under basic or neutral conditions gives rise to the formation of a variety of functionalized α-chloroamides. The resulting products were obtained as solids in moderate to good yields, upon precipitation and isolation by filtration.
Harte, Andrew J.,Gunnlaugsson, Thorfinnur
p. 6321 - 6324
(2007/10/03)
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