- Method for synthesizing R type aminoindane
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The invention discloses a method for synthesizing R type aminoindane, namely R-5,6-dimethoxy-1-amino indan. The method specifically includes the steps that under the action of a catalyst, 5,6-dimethoxy-1-amino indanone is reduced and aminated to generate racemized 5,6-dimethoxy-1-amino indan, 5,6-dimethoxy-1-amino indan is combined with a racemization catalyst by means of lipase for dynamic kinetic resolution, and R-5,6-dimethoxy-1-amino indan is obtained. The method has the advantages of being easy to operate, wide in raw material source, good in product yield, high in resolution product optical purity and the like.
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Paragraph 0006; 0009
(2017/04/03)
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- Indane dimerization products obtained by treatment of N-acylindan-1-amines with ethyl polyphosphate (EPP)
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This report describes the diverse dimeric products obtained by treatment of N-acylindan-1-amines with ethyl polyphosphate in chloroform-diethyl ether solution at 80°C for 8 h. Possible mechanisms for such reactions are discussed.
- Moglioni, Albertina G.,Tombari, Dora G.,Moltrasio Iglesias, Graciela Y.
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p. 3459 - 3462
(2007/10/03)
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