- KAl(SO4)2·12H2O (alum) a reusable catalyst for the synthesis of some 4-substituted coumarins via Pechmann reaction under solvent-free conditions
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A simple, efficient, and practical procedure for the Pechmann condensation using KAl(SO4)2·12H2O (alum) as a non-toxic, reusable, inexpensive, and easily available catalyst is described under solvent-free condition at 65°C. These improved reaction conditions allow the preparation of a wide variety of some new substituted coumarins in high yields (86-96%) and purity under mild reaction conditions. Compared to the classical Pechmann condensation, this new method consistently has the advantage of high yields.
- Azizian, Javad,Mohammadi, Ali A.,Bidar, Ilyar,Mirzaei, Peiman
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experimental part
p. 805 - 808
(2009/09/25)
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