Prenylated xanthones as potential antiplasmodial substances
Mangostin, the major xanthone of Garcinia mangostana, and a series of synthetic derivatives were investigated for their in vitro antiplasmodial activity against Plasmodium falciparum. Mangostin itself showed moderate activity, but prenylated xanthones containing alkylamino functional groups exhibited quite potent antiplasmodial activity. Some structure-activity relationships are proposed. Georg Thieme Verlag KG Stuttgart.
Mahabusarakam, Wilawan,Kuaha, Kunnika,Wilairat, Prapon,Taylor, Walter C.
Cytotoxic and NF-κB inhibitory constituents of the stems of Cratoxylum cochinchinense and their semisynthetic analogues
A new caged xanthone (1), a new prenylxanthone (2), seven known xanthones, and a known sterol glucoside were isolated from the stems of Cratoxylum cochinchinense, collected in Vietnam. Compounds 1 and 2 were determined structurally by analysis of their sp
Ren, Yulin,Matthew, Susan,Lantvit, Daniel D.,Ninh, Tran Ngoc,Chai, Heebyung,Fuchs, James R.,Soejarto, Djaja D.,De Blanco, Esperanza J. Carcache,Swanson, Steven M.,Kinghorn, A. Douglas
experimental part
p. 1117 - 1125
(2011/07/30)
More Articles about upstream products of 925705-36-8