Studies towards the identification of a new generation of atypical antipsychotic agents
A rational structure-activity relationship study around compound (1) is reported. The lead optimisation programme led to the identification of sulfonamide (25), a molecule combining dopamine D2/D3 receptor antagonism with serotonin 5
Garzya, Vincenzo,Forbes, Ian T.,Gribble, Andrew D.,Hadley, Mike S.,Lightfoot, Andrew P.,Payne, Andrew H.,Smith, Alexander B.,Douglas, Sara E.,Cooper, David G.,Stansfield, Ian G.,Meeson, Malcom,Dodds, Emma E.,Jones, Declan N.C.,Wood, Martyn,Reavill, Charlie,Scorer, Carol A.,Worby, Angela,Riley, Graham,Eddershaw, Peter,Ioannou, Chris,Donati, Daniele,Hagan, Jim J.,Ratti, Emiliangelo A.
p. 400 - 405
(2007/10/03)
More Articles about upstream products of 956140-28-6