- Compound, luminescent layer guest material, organic electroluminescent device and display device
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The invention provides a compound as shown in a general formula (I). The compoundcan be used for an organic electroluminescent device as a guest material of a luminescent layer. The compound comprises a natural heterocyclic ring and iridium (Ir) coordinated structure, and the light emitting wavelength of the compound can be effectively regulated and controlled. When the compound is used as a guest material of a light-emitting layer, the light-emitting efficiency and the light stability of the organic electroluminescent device can be improved. In addition, the compound provided by the invention is small in molecular weight, is applied to a light-emitting layer, is relatively low in evaporation temperature, and is beneficial to processing. The invention also provides a luminescent layer guest material containing the compound shown in the general formula (I), an organic electroluminescent device and a display device.
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Paragraph 0170-0174
(2021/06/22)
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- Corrigendum: Synthesis of Tetracyclic Fused Quinolines via a Friedel-Crafts and Beckmann Ring Expansion Sequence (Journal of Physical Chemistry (2019) DOI: 10.1071/CH19363_CO)
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The publisher wishes to draw the reader’s attention to an error in the above paper. On the second page, right column, first line, ‘‘PhNHNH2 HCl’’ should be ‘PhNHNH2.
- Abd El-Aal, Hassan A. K.,El-Emary, Talaat I.
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- Fragment-based discovery of pyrimido[1,2-B]indazole PDE10A inhibitors
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In this study, we report the identification of potent pyrimidoindazoles as phosphodiesterase10A (PDE10A) inhibitors by using the method of fragment-based drug discovery (FBDD). The pyrazolopyridine derivative 2 was found to be a fragment hit compound which could occupy a part of the binding site of PDE10A enzyme by using the method of the X-ray co-crystal structure analysis. On the basis of the crystal structure of compound 2 and PDE10A protein, a number of compounds were synthesized and evaluated, by means of structure-activity relationship (SAR) studies, which culminated in the discovery of a novel pyrimidoindazole derivative 13 having good physicochemical properties.
- Chino, Ayaka,Seo, Ryushi,Amano, Yasushi,Namatame, Ichiji,Hamaguchi, Wataru,Honbou, Kazuya,Mihara, Takuma,Yamazaki, Mayako,Tomishima, Masaki,Masuda, Naoyuki
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p. 286 - 294
(2018/03/13)
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- Tridentate N-donor palladium(II) complexes as efficient coordinating quadruplex DNA binders
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Fifteen complexes of palladium, platinum, and copper, featuring five different N-donor tridentate (terpyridine-like) ligands, were prepared with the aim of testing their G-quadruplex-DNA binding properties. The fluorescence resonance energy transfer melti
- Largy, Eric,Hamon, Florian,Rosu, Frederic,Gabelica, Valerie,De Pauw, Edwin,Guedin, Aurore,Mergny, Jean-Louis,Teulade-Fichou, Marie-Paule
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p. 13274 - 13283
(2012/02/03)
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- Total synthesis of streptonigrone
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(Chemical Equation Presented) A total synthesis of streptonigrone, 1, is described, which incorporates a one-step synthesis of substituted pyridones devised in our laboratory. Other aspects of the synthesis that differentiate the present approach from previous ones are the use of a Conrad-Limpach reaction, rather than the customary Friedlaender methodology, to assemble the quinoline segment of 1, and the implementation of an anionic sequence for the functionalization of a key pyridone intermediate.
- Chan, Bryan K.,Ciufolini, Marco A.
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p. 8489 - 8495
(2008/02/13)
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- Tricyclic quinoxalinediones
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Tricyclic quinoxalinediones of the formula: STR1 wherein X is alkyl, halogen, cyano, trifluoromethyl, nitro, hydroxy, amino, etc.; R 1 is H, etc.; R 2 is H, alkyl, cycloalkyl, alkenyl, alkynyl, cycloalkylalkyl, arylalkyl, substituted arylalkyl, aryl, or substituted aryl; W is H, CO 2 R 3, CO 2 Y, CONR 3 R 4, CONR 3 Y, CON(OR 3)R 4, COR 3, CN, tetrazolyl, or substituted alkyl; R 3 and R 4 independently are H, alkyl, cycloalkyl, alkenyl, alkynyl, etc.; Y is mono-substituted alkyl or di-substituted alkyl; and n is an integer 0 or 1, or a pharmaceutically acceptable salt thereof, which are useful as a selective antagonist of glutamate receptor for the treatment or prevention of various diseases in animals including human being, for example, minimizing damage of central nervous system induced by ischaemic or hypoxylic conditions, treatment and/or prevention of neurodegenerative disorders, and further analgesics, antidepressants, anxiolitics, and anti-schizophrenics.
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