Synthetic carbapenem antibiotics III. 1-Methyl thienamycin
Total syntheses of 1α- and 1β-methyl thienamycin are reported. 1β-Methyl thienamycin retains the antibacterial activity of thienamycin and is highly resistant to hydrolysis by HPD-1 enzyme.
Shih,Cama,Christensen
p. 587 - 590
(2007/10/02)
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