Isothiocyanates as H2S Donors Triggered by Cysteine: Reaction Mechanism and Structure and Activity Relationship
Isothiocyanates are reported as H2S donors, yet the mechanisms are not clear. Herein, we reported that isothiocyanates (ITCs, R-NCS) rapidly formed adducts with cysteine. These adducts underwent intramolecular cyclization followed by releasing
A facile one-pot synthesis and heterocyclisation of (R)-2-amino-3- ((aroylcarbamothioyl)thio)propanoic acids
A series of (R)-2-amino-3-((aroylcarbamothioyl)thio)propanoic acid derivatives have been synthesised by a one-pot, threecomponent reaction of L-cysteine with ammonium thiocyanate in the presence of various acid chlorides under solvent-free conditions in excellent yields. These compounds were converted to (R)-2-thioxothiazolidine-4-carboxylic acid in water under reflux conditions.
Mohebat, Razieh,Kafrizi, Elahe
p. 172 - 174
(2014/04/17)
Site-specific conjugation of RAFT polymers to proteins via expressed protein ligation
Site-specific protein conjugates with RAFT polymers were synthesized using expressed protein ligation. Stable micelles were formed from both linear block copolymer and Y-shaped conjugates.
Xia, Yan,Tang, Shengchang,Olsen, Bradley D.
supporting information
p. 2566 - 2568
(2013/04/23)
The preparation of pure 2-thio-thiazolidine-4-carboxylic-acid (TTCA) as a reference standard for carbon disulfide exposure tests
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Rosier,Simonds,Van Peteghem,Vanhoorne
p. 397 - 402
(2007/10/02)
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