- Synthesis method of citrazinic acid
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The invention belongs to the technical field of compound preparation and particularly relates to a synthesis method of citrazinic acid. The method adopts a hydrothermal reaction method of citric acidand urea and particularly comprises the steps of dissolving citric acid and urea in deionized water, performing ultrasound dispersion and intensive mixing, performing a hydrothermal reaction under a certain temperature condition in a reaction kettle, performing high-speed centrifugation on reaction liquid at last, removing a supernate, and drying an obtained yellow precipitate, namely a citrazinicacid product with good color, high yield and high purity. The method is mild in reaction condition, and simple to operate; one-step sulfuric acid hydrolysis is required only, and the product is highin purity (greater than 96%) and productivity (70-85%).
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Paragraph 0010; 0012; 0013
(2018/07/06)
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- PROCESS FOR PRODUCTION OF 2-HYDROXY-4-SUBSTITUTED PYRIDINES
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A process for preparing a 2-hydroxy-4-substituted pyridine compound using a microbiological method, a novel microorganism, and a novel compound are provided. According to the process, a function of a microorganism or a product obtained therefrom is exerted on a 4-substituted pyridine of the general formula (1): wherein R is a methyl group, a carboxyl group, a carbamoyl group, a hydroxyiminomethyl group or a cyano group, to obtain the corresponding 2-hydroxy-4-substituted pyridine compound. The novel microorganisms are the Delftia species YGK-A649 (FERM BP-10389), Delftia species YGK-C217 (FERM BP-10388), or Acidovorax species YGK-A854 (FERM BP-10387) and the novel compound is a 2-hydroxy-4-pyridinaldoxime.
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Page/Page column 9-10
(2008/06/13)
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