182344-21-4 Usage
Description
Boronic acid, (4-hydroxy-3-methoxyphenyl)(9CI) is an organic compound that belongs to the class of boronic acids. It is characterized by the presence of a hydroxyl and methoxy group on the phenyl ring, which provides it with unique chemical properties and reactivity. Boronic acid, (4-hydroxy-3-methoxyphenyl)(9CI) is known for its ability to form stable complexes with various molecules, making it a versatile reagent in organic synthesis and other chemical processes.
Uses
Used in Pharmaceutical Industry:
Boronic acid, (4-hydroxy-3-methoxyphenyl)(9CI) is used as a reagent for the synthesis of 4-arylcoumarins, which possess antiprotozoal activity. These compounds are of significant interest in the development of new drugs to combat parasitic infections, such as malaria and leishmaniasis. The synthesis of these bioactive molecules is typically achieved through the Suzuki-Miyaura cross-coupling reaction, which involves the use of this boronic acid as a key intermediate.
Used in Chemical Research:
In the field of chemical research, Boronic acid, (4-hydroxy-3-methoxyphenyl)(9CI) is utilized as a reagent in the direct palladium-catalyzed C-H functionalization of benzoquinones. This reaction is an important method for the selective functionalization of aromatic compounds, allowing for the introduction of various functional groups at specific positions on the benzene ring. The use of this boronic acid in this process enables the synthesis of a wide range of complex organic molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Overall, Boronic acid, (4-hydroxy-3-methoxyphenyl)(9CI) is a valuable compound in the fields of pharmaceuticals and chemical research, owing to its unique chemical properties and its role in the synthesis of biologically active molecules and complex organic compounds. Its applications in these areas highlight the importance of continued research and development in the field of organic chemistry, as well as the potential for further discoveries and innovations in the future.
Check Digit Verification of cas no
The CAS Registry Mumber 182344-21-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,3,4 and 4 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 182344-21:
(8*1)+(7*8)+(6*2)+(5*3)+(4*4)+(3*4)+(2*2)+(1*1)=124
124 % 10 = 4
So 182344-21-4 is a valid CAS Registry Number.
182344-21-4Relevant articles and documents
Simple preparation of phenylpropenoid β-D-glucopyranoside congeners by Mizoroki-Heck type reaction using organoboron reagents
Kishida, Masashi,Akita, Hiroyuki
, p. 10559 - 10568 (2007/10/03)
Palladium(II)-catalyzed carbon-carbon bond formation between allyl 2,3,4,6-tetra-O-acetyl-β-d-glucopyranoside (3) and arylboronic acid congeners gave the corresponding cinnamyl 2,3,4,6-tetra-O-acetyl- β-d-glucopyranosides (4a-m) in good yield. Among them, coupling products 4a-m were converted to not only the naturally occurring phenylpropenoid β-d-glucopyranoside analogues (1a-e) but also the unnaturally ones (1f-m).
