Basic information
- Name:
Catharanthine
- CAS No.:
2468-21-5
- Molecular Structure:
- Formula:
- C21H24N2O2
- Synonyms:
- Catharanthine(6CI,7CI,8CI);(+)-3,4-Didehydrocoronaridine;(+)-Catharanthine;Ibogamine-18-carboxylicacid, 3,4-didehydro-, methyl ester, (2a,5b,6a,18b)-;Catharanthine, (+)-;
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Chemistry
Molecular Structure of Catharanthine (CAS NO.2468-21-5):
Product Name: (+)-Catharanthine
Molecular Formula: C21H24N2O2
Molecular Weight: 336.427460 g/mol
Appearance: off-white to pale beige solid
Melting Point: 138-1400 °C
Density: 1.27 g/cm3
Flash Point: 251.1 °C
Enthalpy of Vaporization: 75.83 kJ/mol
Boiling Point: 491.5 °C at 760 mmHg
Vapour Pressure: 8.33E-10 mmHg at 25 °C
Water Solubility: 72.28 mg/L at 25 °C
EINECS: 219-586-6
Synonyms of Catharanthine (CAS NO.2468-21-5): (+)-3,4-didehydrocoronaridine ; 18-beta)-lph ; Catharanthin ; Ibogamine-18-carboxylicacid,3,4-didehydro-,methylester,(2-alpha,5-beta,6-a ; Methyl(2-alpha,5-beta,6-alpha,18-beta)-3,4-didehydroibogamine-18-carboxylate ; Catharanthine;catharanthine base ; Methyl (2alpha,5beta,6alpha)-3,4-didehydroibogamine-18beta-carboxylate
Categories of Catharanthine (CAS NO.2468-21-5): Heterocycles ; Chiral Reagents ; Intermediates & Fine Chemicals ; Pharmaceuticals
Uses
Catharanthine (CAS NO.2468-21-5) is used as a precursor of Vinblastine-type alkaloids.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | > 800mg/kg (800mg/kg) | Biochemical Pharmacology. Vol. 26, Pg. 1213, 1977. |
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