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Cas Database |
| Name |
Cefamandole |
EINECS | 252-030-0 |
| CAS No. | 34444-01-4 | Density | 1.75 g/cm3 |
| PSA | 201.14000 | LogP | 0.10320 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C18H18 N6 O5 S2 | Boiling Point | °Cat760mmHg |
| Molecular Weight | 462.51 | Flash Point | °C |
| Transport Information | N/A | Appearance | White to off-white powder |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[(hydroxyphenylacetyl)amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,[6R-[6a,7b(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-hydroxyphenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,(6R,7R)- (9CI);3-(1-Methyltetrazol-5-ylthiomethyl)-7-D-mandelamido-3-cephem-4-carboxylic acid;CMT; Cefadole; Cefamandol; Cefamandole; Cephadole; Cephamandole; L-Cefamandole |
Article Data | 8 |
Cefamandole Chemical Properties
Chemistry informtion about Cephamandole (CAS NO.34444-01-4) is:
IUPAC Name: Pentyl nitrite
Synonyms: Cefamandole ; (R*)))- ; 5-Thia-1-Azabicyclo(4.2.0)Oct-2-Ene-2-Carboxylicacid,7-((Hydroxyphenylacetyl) ; Amino)-3-(((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-,(6r-(6-Alpha,7-Beta ; Cefadole ; Cefamandol ; Cephadole ; Cephamandole
MF: C18H18N6O5S2
MW: 462.5
EINECS: 252-030-0
Density: 1.75 g/cm3
Following is the molecular structure of Cephamandole (CAS NO.34444-01-4) is:
Cefamandole Uses
Cephamandole (CAS NO.34444-01-4) (INN, also known as cephamandole ) is a second-generation broad-spectrum cephalosporin antibiotic. The clinically used form of cefamandole is the formate ester cefamandole nafate, a prodrug which is administered parenterally.It is no longer available in the United States.
Cefamandole Safety Profile
Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx.
Cefamandole Specification
The chemical structure of Cephamandole (CAS NO.34444-01-4) , like that of several other cephalosporins, contains an N-methylthiotetrazole (NMTT or 1-MTT) side chain. As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse), due to inhibition of aldehyde dehydrogenase.
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