Basic information
- Name:
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[[(2S)-2-amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:1), (6R,7S)-
- Superlist Name:
- Cefminox sodium
- CAS No.:
75498-96-3
- Molecular Structure:
![Molecular Structure of 75498-96-3 (5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[[(2S)-2-amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:1), (6R,7S)-)](http://www.lookchem.com/300w/2010/0624/75498-96-3.jpg)
- Formula:
- C16H20N7NaO7S3
- Molecular Weight:
- 541.56
- Deleted CAS:
- 78345-56-9
- Synonyms:
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[(2-amino-2-carboxyethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,monosodium salt, [6R-[6a,7a,7(S*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[[(2S)-2-amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,monosodium salt, (6R,7S)- (9CI);Cefminox sodium;Cefminox sodium salt;Meicelin;
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Chemistry
IUPAC Name: Sodium (6R,7S)-7-[[2-(2-amino-3-hydroxy-3-oxopropyl)sulfanylacetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Systematic of Cefminox sodium (CAS NO.75498-96-3): Antibiotic MT-141 ; Meicelin ; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, monosodium salt, (6R-(6-alpha,7-alpha))-
CAS NO: 75498-96-3
Classification Code: Drug / Therapeutic Agent ; Reproductive Effect
Molecular Formula of Cefminox sodium (CAS NO.75498-96-3): C16H20N7NaO7S3
Molecular Weight: 541.5575
Molecular Structure:
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H bond acceptors: 14
H bond donors: 5
Freely Rotating Bonds: 12
Polar Surface Area of Cefminox sodium (CAS NO.75498-96-3): 236.19 Å2
Uses
Cefminox sodium (CAS NO.75498-96-3) is used as cephalosporin antibiotic fungi.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intramuscular | 8200mg/kg (8200mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984. |
| mouse | LD50 | intravenous | 5200mg/kg (5200mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984. |
| mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 18, Pg. 1030, 1987. | |
| rat | LD50 | intramuscular | 9600mg/kg (9600mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984. |
| rat | LD50 | intraperitoneal | 8550mg/kg (8550mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984. |
| rat | LD50 | intravenous | 5700mg/kg (5700mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984. |
| rat | LD50 | oral | > 15gm/kg (15000mg/kg) | Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984. | |
| rat | LD50 | subcutaneous | > 15gm/kg (15000mg/kg) | Japanese Journal of Antibiotics. Vol. 37, Pg. 847, 1984. |