Ceftiofur sodium (104010-37-9),Ceftiofur sodium (104010-37-9) Manufacturers & Suppliers,Synthesis,MSDS

Basic information

Name:
Ceftiofur sodium
CAS No.:
104010-37-9
Molecular Structure:
Formula:
C₁₉H₁₆N₅NaO₇S₃
Molecular Weight:
545.55
Synonyms:
Ceftiofur sodium salt;Sodium ceftiofur;(6R-(6alpha,7beta(Z))-7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt;CCRIS 7601;Naxcel;Sodium (6R,7R)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate, 7(sup 2)-(Z)-(O-methyloxime), 2-furoate (ester);
Density:
1.81 g/cm³
Solubility:
freely soluble In Water
Appearance:
off-white or yellowish crystalline powder

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Chemistry

The Molecular Structure of Ceftiofur sodium (CAS NO.104010-37-9):

Empirical Formula: C₁₉H₁₆N₅NaO₇S₃
Molecular Weight: 545.5444
IUPAC: sodium (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
PHYSICAL STATE OF CEFTIOFUR SODIUM: White to off-white powder
STABILITY OF CEFTIOFUR SODIUM: Stable under ordinary conditions
Product Categories: APIs;cephalosporins antibiotics
Synonyms: Ceftiofur monosodium salt ; Ceftiofur sodium [USAN] ; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo-, monosodium salt, (6R-(6alpha,7beta(Z)))- ; CCRIS 7601 ; CM 31-916 ; Ceftiofur sodium ; Naxcel ; Sodium (6R,7R)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate, 7(sup 2)-(Z)-(O-methyloxime), 2-furoate (ester) ; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo-, monosodium salt, (6R-(6alpha,7beta(Z)))- Ceftiofur sodium

Uses

CEFTIOFUR Sodium (CAS NO.104010-37-9) can be used as veterinary drug raw materials.

Toxicity Data With Reference

Acute toxicity LD₅₀: 7760 mg/kg, Rat, Oral
LD₅₀: 927 mg/kg, Rat, Intraperitoneal
LD₅₀: 8.3 mg/kg, Rat, Inhalation Sensitization
May cause sensitization by inhalation and skin contact.

Standards and Recommendations

ASSAY: 98.0%
WATER: 4.0% max
RELATED SUBSTANCE: 2.0% max
HEAVY METALS: 20ppm max

Specification

Steps to be Taken in Case Material is Released or Spilled:
Wear respirator, chemical safety goggles, rubber boots and heavy rubber gloves. Sweep up, place in a bag and hold for waste disposal. Avoid raising dust.
Waste Disposal Method:
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state and local environmental regulations.
Precautions to Be Taken in Handling and Storage:
Keep tightly closed. Store in a cool dry place.