- Nenitzescu Indole Synthesis
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Nenitzescu Synthesis
C. D. Nenitzescu, Bull. Soc. Chim. Romania 11, 37 (1929).
Synthesis of 5-hydroxyindole derivatives by condensation of with β-aminocrotonic esters:
Reviews: R. K. Brown in The Chemistry of Heterocyclic Compounds, W. J. Houlihan, Ed. (Wiley, New York, 1972) p 413; G. R. Allen, Jr., Org. React. 20, 337 (1973). Synthetic applications: U. Kuecklander, W. Huehnermann, Arch. Pharm. 312, 515 (1979); J. L. Bernier, J. P., Henichart, J. Org. Chem. 46, 4197 (1981). M. Kinugawa et al., J. Chem. Soc. Perkin Trans. I 1995, 2677; J. M. Pawlak et al., J. Org. Chem. 61, 9055 (1996).
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