(or AHA or Lithostat), with the CAS registry number , has its IUPAC name of N-hydroxyacetamide. This chemical is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections.

Following are the detailed information of Acetohexamide:
1). Indication of Acetohydroxamic Acid: Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
2). Pharmacodynamics of Acetohydroxamic Acid: Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly.
3). Mechanism of action Acetohydroxamic Acid reversibly inhibits the bacterial enzyme urease. This inhibits the hydrolysis of urea and production of ammonia in urine infected with urea-splitting organisms, leading to a decrease in pH and ammonia levels. As antimicrobial agents are more effective in such conditions, the effectiveness of these agents is amplified, resulting in a higher cure rate.
4). Absorption of Acetohydroxamic Acid: Well absorbed from the GI tract following oral administration.