Since 1921, Organic Syntheses has provided the chemistry community with detailed, reliable, and carefully checked procedures for the synthesis of organic compounds. Some procedures describe practical methods for the preparation of specific compounds of interest, while other procedures illustrate important synthetic methods with general utility. Each procedure is written in considerably more detail as compared to typical experimental procedures in other journals, and each reaction and all characterization data has been carefully "checked" for reproducibility in the laboratory of a member of the Board of Editors.
 
Organic Syntheses procedures may be accessed either via the tables of contents of individual volumes ("journal mode") or by conducting structure and keyword searches ("database mode"). "Database mode" allows users to simultaneously search all volumes of Organic Syntheses by keywords or by inputting structures and substructures. Structure searching requires the ChemDraw plugin which can be downloaded according to the instructions found in the left margin. Articles from the current volume of Organic Syntheses that are not yet incorporated in the searchable database can be accessed on the "Org Syn Express" page.

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