PK-9084 (CAS NO.: ), with its systematic name of , 2-phenyl-4-(2-(3-piperidinyl)ethyl)-, could be produced through many synthetic methods.

Following is one of the reaction routes: Ethyl 2-phenylquinoline-4-carboxylate (I) could react with N-benzoylpipepidine-3-acetic acid ethyl ester (II) to produce 2-phenyl-4-[2-(3-piperidyl)acetyl]quinoline (III) in the presence of potassium hydride in THF, and then the yield compound is reduced with hydrazine in dietyleneglycol at 180 C.