Cholestyramine

Reported in EPA TSCA Inventory.

The Cholestyramine with cas registry number of 11041-12-6 also has other registry numbers including 58391-37-0 and 9007-26-5. Its EINECS registry number is 234-270-8. Its molecular formula has not been unspecified. And no descriptors have found for this chemical. It is white to buff-colored fine powder with odorless or a slight amine odor. It is insoluble in water.

This chemical belongs to classification codes which include (1)Anion exchange resins; (2)Anticholesteremic agents; (3)Antihyperlipidemic; (4)Antilipemic Agents; (5)Antimetabolites; (6)Human Data; (7)Ion Exchange Resins; (8)Ion-exchange resin [bile salts]; (9)Reproductive Effect; (10)Tumor data. It is also known as (1)HSDB 7219; (2)Locholest; (3)Locholest Light; (4)Polystyrene benzyltrimethylaminonium chloride; (5)Prevalite; (6)Quantalan; (7)Questran; (8)Questran Light; (9)UNII-4B33BGI082.

Uses of Cholestyramine: this compound has been used as a drug for the treatment of typeⅡhyperlipidemia, atherosclerosis and Itching caused by Cirrhosis and gallstone disease. There is a disadvantage about this drug. It has to be used in a large amount during the treatment. About 2% of patients have the gastrointestinal tract.

When you are using this chemical, please be cautious about it as the following:
Low toxicity by ingestion. Questionable human carcinogen producing colon tumors. An experimental teratogen. Other experimental reproductive effects. Toxic effects by ingestion: acidosis and nosebleeds. When heated to decomposition it emits acrid smoke and irritating fumes.

The toxicity data is as follows: