- Clomethiazole
- Clomethiazole ethane-1,2-disulfonate
- 5334-59-81H-Pyrazolo[3,4-d]pyrimidine,4-chloro-1-(4-chlorophenyl)-
- 53347-39-0Hydrazinecarbothioamide, N-pentyl-
- 53347-40-3Hydrazinecarbothioamide,N-hexyl-
- 53348-04-29,10-Phenanthrenediamine
- 53348-05-33,6-dibromo-phenanthrene-9,10-dione
- 53348-92-82H-1-Benzopyran-2-one,4-amino-
- 53-34-9Pregna-1,4-diene-3,20-dione,6-fluoro-11,17,21-trihydroxy-, (6a,11b)-
- 533-49-3Butanal,2,3,4-trihydroxy-, (2S,3S)-
- 53-35-0Pregn-4-ene-3,20-dione,6,11,17,21-tetrahydroxy-, (6b,11b)-
- 53350-26-84H-1-Benzopyran-4-one,5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Clomethiazole |
EINECS | 208-565-7 |
| CAS No. | 533-45-9 | Density | 1.219 g/cm3 |
| PSA | 41.13000 | LogP | 3.03480 |
| Solubility | N/A | Melting Point |
127-128 °C |
| Formula | C6H8ClNS | Boiling Point | 245.774 °C at 760 mmHg |
| Molecular Weight | 161.655 | Flash Point | 102.441 °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
4-Methyl-5-(b-chloroethyl)thiazole;5-(2-Chloroethyl)-4-methylthiazole;5-(b-Chloroethyl)-4-methylthiazole;Chlorethiazol;Chlorethiazole;Chlormethiazol;Chlormethiazole;Clomethiazole;Clomethiazolum;Distraneurin;Emineurina;Somnevrin; |
Article Data | 19 |
Clomethiazole Synthetic route
| Conditions | Yield |
|---|---|
| With thionyl chloride for 3h; Reflux; | 98% |
| With thionyl chloride for 2h; Heating; | 96% |
| With phosphorus pentachloride In dichloromethane for 3h; Heating; | 95% |
- 533-45-9
chlormethiazole
| Conditions | Yield |
|---|---|
| With hydrogenchloride; dihydrogen peroxide |
- 853261-35-5
5-(2-ethoxyethyl)-4-methylthiazole
- 533-45-9
chlormethiazole
| Conditions | Yield |
|---|---|
| With hydrogenchloride |
- 663179-27-9
5-ethoxy-3-chloro-pentan-2-one
- 533-45-9
chlormethiazole
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 2: concentrated aqueous HCl View Scheme |
- 663179-24-6
2-(2-ethoxy-ethyl)-2-chloro-acetoacetic acid ethyl ester
- 533-45-9
chlormethiazole
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: glacial acetic acid; H2SO4 3: concentrated aqueous HCl View Scheme |
- 13045-13-1
3-chloro-3-acetylpropanol
- 533-45-9
chlormethiazole
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: ethanol 2: concentrated aqueous HCl View Scheme |
- 58371-98-5
3, 5-dichloro-2-pentanone
- 533-45-9
chlormethiazole
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: ethanol / anschliessend Behandeln mit H2O 2: H2O2; concentrated aqueous HCl View Scheme |
| Conditions | Yield |
|---|---|
| In N,N-dimethyl-formamide at 20 - 80℃; for 8h; | 98% |
- 533-45-9
chlormethiazole
- 77-78-1
dimethyl sulfate
- 78919-46-7
5-(β-Chloroethyl)-3,4-dimethylthiazolium methyl sulfate
| Conditions | Yield |
|---|---|
| In acetone at 20℃; for 24h; | 85% |
- 533-45-9
chlormethiazole
- 1074-82-4
potassium phtalimide
- 36956-91-9
4-methyl-5-(β-phthalimidoethyl)thiazole
| Conditions | Yield |
|---|---|
| In N,N-dimethyl-formamide at 100 - 105℃; for 2h; | 67% |
| In N,N-dimethyl-formamide (heating); |
Clomethiazole Chemical Properties
5-(2-chloroethyl)-4-methylthiazole (533-45-9) is also named as clomethiazole;chlormethiazole;;ChlormethiazoleHCl;5-(2-Chlorethyl)-4-methylthiazole hydrochloride;Chlorethiazole;Clomethiazolum,and so on.
CAS: 533-45-9
Molecular Formula: C6H8ClNS
Molecular Weight: 161.65
Molecular structure:
EINECS: 208-565-7
Index of Refraction: 1.545
Molar Refractivity: 41.95 cm3
Molar Volume: 132.6 cm3
Polarizability: 16.63 10-24cm3
Surface Tension: 41.8 dyne/cm
Density: 1.218 g/cm3
Flash Point: 102.4 °C
Enthalpy of Vaporization: 46.33 kJ/mol
Boiling Point: 245.8 °C at 760 mmHg
Vapour Pressure: 0.0442 mmHg at 25°C
Clomethiazole Uses
Clomethiazole Toxicity Data With Reference
| 1. | orl-mus LD50:2110 mg/kg | JMCMAR Journal of Medicinal Chemistry. 7 (1964),167. | ||
| 2. | ipr-mus LD50:190 mg/kg | APSXAS Acta Pharmaceutica Suecdca. 8 (1971),39. | ||
| 3. | ivn-mus LD50:94 mg/kg | APSXAS Acta Pharmaceutica Suecdca. 7 (1970),423. |
RTECS: XJ3850000
Clomethiazole Safety Profile
What can I do for you?
Get Best Price
