- 2058-58-4Asparagine D-form
- 205871-49-4[1,1'-Biphenyl]-4-carboxylicacid, 2'-formyl-
- 205871-52-9[1,1'-Biphenyl]-3-carboxylicacid, 2'-formyl-
- 205873-26-31,2-Ethanediamine,N,N'-dimethyl-1,2-bis[3-(trifluoromethyl)phenyl]-,[S-(R*,R*)]- (9CI)
- 205873-28-51H-Indole-2-carboxylicacid, 5-(methylsulfonyl)-, methyl ester
- 205873-56-9Benzoic acid,3,4-bis(acetylamino)-
- 205873-58-1Indole-7-carboxylic acid ethyl ester
- 2058-74-41H-Indole-2,3-dione,1-methyl-
- 2058-94-8Undecanoic acid,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heneicosafluoro-
- 20590-45-8b-D-Glucopyranosyl isothiocyanate,2-(acetylamino)-2-deoxy-, 3,4,6-triacetate
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
| Name |
Clothiapine |
EINECS | N/A |
| CAS No. | 2058-52-8 | Density | 1.33g/cm3 |
| PSA | 44.14000 | LogP | 3.44170 |
| Solubility | N/A | Melting Point |
121-123℃ |
| Formula | C18H18 Cl N3 S | Boiling Point | 483.8°Cat760mmHg |
| Molecular Weight | 343.88 | Flash Point | 246.4°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl−, NOx, and SOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
2-Chloro-11-(4-methyl-1-piperazinyl)dibenzo[b,f][1,4]thiazepine;2-Chloro-11-(4-methylpiperazino)dibenzo[b,f][1,4]thiazepine; Clothiapin;Clothiapine; Clotiapine; Deliton; Entumine; Etumine; HF 2159; LW 2159 |
Clothiapine Chemical Properties
Empirical Formula: C18H18ClN3S
Molecular Weight: 343.8736 g/mol
EINECS: 218-162-8
Index of Refraction: 1.69
Density: 1.33 g/cm3
Flash Point: 246.4 °C
Enthalpy of Vaporization: 74.9 kJ/mol
Boiling Point: 483.8 °C at 760 mmHg
Vapour Pressure: 1.62E-09 mmHg at 25 °C
Structure of Clothiapine (CAS NO.2058-52-8):
IUPAC Name of Clothiapine (CAS NO.2058-52-8): 8-Chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,5]benzothiazepine
Clothiapine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | oral | 150mg/kg (150mg/kg) | Toxicology and Applied Pharmacology. Vol. 14, Pg. 657, 1969. | |
| mouse | LD50 | intramuscular | 160mg/kg (160mg/kg) | Drugs in Japan Vol. 6, Pg. 234, 1982. | |
| mouse | LD50 | intravenous | 46mg/kg (46mg/kg) | Drugs in Japan Vol. 6, Pg. 234, 1982. | |
| mouse | LD50 | oral | 270mg/kg (270mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 841, 1965. | |
| mouse | LD50 | subcutaneous | 348mg/kg (348mg/kg) | Drugs in Japan Vol. 6, Pg. 234, 1982. | |
| rat | LD50 | intramuscular | > 300mg/kg (300mg/kg) | Drugs in Japan Vol. 6, Pg. 233, 1982. | |
| rat | LD50 | intravenous | 47mg/kg (47mg/kg) | Drugs in Japan Vol. -, Pg. 404, 1995. | |
| rat | LD50 | oral | 280mg/kg (280mg/kg) | Drugs in Japan Vol. 6, Pg. 234, 1982. | |
| rat | LD50 | subcutaneous | > 500mg/kg (500mg/kg) | Drugs in Japan Vol. 6, Pg. 233, 1982. |
Clothiapine Safety Profile
Poison by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition Clothiapine (CAS NO.2058-52-8) emits very toxic fumes of Cl−, NOx, and SOx.
Clothiapine Specification
Clothiapine ,its cas register number is 2058-52-8. It also can be called Clotiapine ; Entumine ; and Dibenzo(b,f)(1,4)thiazepine, 2-chloro-11-(4-methyl-1-piperazinyl)- . It is an atypical antipsychotic of the dibenzothiazepine chemical class and is structurally analogous to quetiapine.
What can I do for you?
Get Best Price
