Basic Information | Post buying leads | Suppliers |
Name |
Coben |
EINECS | N/A |
CAS No. | 24699-40-9 | Density | N/A |
PSA | 19.37000 | LogP | 4.31400 |
Solubility | N/A | Melting Point |
183-185° |
Formula | C19H25 N3 . Cl H | Boiling Point | N/A |
Molecular Weight | 331.93 | Flash Point | N/A |
Transport Information | N/A | Appearance | N/A |
Safety | Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and HCl. | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
2-Pyridinemethanamine,N-phenyl-N-[2-(1-piperidinyl)ethyl]-, monohydrochloride (9CI); Piperidine,1-[2-[N-(2-pyridylmethyl)anilino]ethyl]-, monohydrochloride (8CI); Coben;N-(2-Picolyl)-N-phenyl-N-(2-piperidinoethyl)amine hydrochloride; Picoperidaminehydrochloride; Picoperine hydrochloride |
Product Name: Coben
Molecular Formula: C19H25N3
Molecular Weight: 295.4219 g/mol
Mol File: 24699-40-9.mol
Index of Refraction: 1.596
Molar Refractivity: 92.41 cm3
Molar Volume: 271.3 cm3
Surface Tension: 48.6 dyne/cm
Boiling point: 448.5 °C at 760 mmHg
Flash Point: 225.1 °C
Density: 1.088 g/cm3
Surface Tension: 48.6 dyne/cm
Enthalpy of Vaporization: 70.71 kJ/mol
Vapour Pressure: 3.08E-08 mmHg at 25 °C
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | intravenous | 25mg/kg (25mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1916, 1969. |
dog | LDLo | oral | 100mg/kg (100mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1916, 1969. |
mouse | LD50 | intraperitoneal | 55500ug/kg (55.5mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
mouse | LD50 | intravenous | 10mg/kg (10mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
mouse | LD50 | oral | 195mg/kg (195mg/kg) | Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 29, Pg. 310, 1970. | |
mouse | LD50 | subcutaneous | 142mg/kg (142mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. |
rat | LD50 | intraperitoneal | 69mg/kg (69mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
rat | LD50 | intravenous | 11500ug/kg (11.5mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. | |
rat | LD50 | oral | 740mg/kg (740mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. |
rat | LD50 | subcutaneous | 480mg/kg (480mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970. |
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and HCl.
Coben ,its CAS NO. is 24699-40-9,the synonyms is -(2-(N-(2-Pyridylmethyl)anilino)ethyl)piperidine hydrochloride ; 1-(2-(Phenyl(2-pyridylmethyl)amino)ethyl)piperidine hydrochloride ; 2-Pyridinemethanamine, N-phenyl-N-(2-(1-piperidinyl)ethyl)-, monohydrochloride ; N-(2-Picolyl)-N-phenyl-N-(2-piperidinoethyl)amine hydrochloride ; N-(2-Piperidinoethyl)-N-(2-pyridylmethyl)aniline hydrochloride ; N-(2-Pyridylmethyl)-N-phenyl-N-2-(piperidinoethyl)amine hydrochloride ; N-Phenyl-N-(2-pyridylmethyl)-2-piperidinoethylamine hydrochloride ; Picoperidamine hydrochloride ; Picoperine HCl ; Picoperine hydrochloride ; Piperidine, 1-(2-(N-(2-pyridylmethyl)anilino)ethyl)-, monohydrochloride ; TAT-3 hydrochloride ; Piperidine, 1-(2-(N-(2-pyridylmethyl)anilino)ethyl)-, hydrochloride .