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Concanavalin A

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Name Concanavalin A EINECS 234-258-2
CAS No. 11028-71-0 Density
Solubility PBS: 5 mg/mL, slightly hazy Melting Point
Formula Unspecified Boiling Point
Molecular Weight Flash Point
Transport Information UN 1170 3/PG 3 Appearance
Safety 36 Risk Codes 10
Molecular Structure Molecular Structure of 11028-71-0 (Concanavalin A) Hazard Symbols HarmfulXn
Synonyms

Con A;Concanavaline A;Lectins, concanavalins A;

 

Specification

The CAS registry number of Concanavalin A is 11028-71-0. It is a lectin (carbohydrate-binding protein) originally extracted from the jack-bean. And it is the first lectin to be available on a commercial basis. In addition, it is a plant mitogen, and is known for its ability to stimulate mouse T-cell subsets giving rise to four functionally distinct T cell populations.

Uses of Concanavalin A: it is widely used in biology and biochemistry to characterize glycoproteins and other sugar-containing entities on the surface of various cells. And it is used to purify glycosylated macromolecules in lectin affinity chromatography. Moreover, it is useful in applications requiring solid-phase immobilization of glycoenzymes.

When you are using this chemical, please be cautious about it as the following:
This chemical is flammable. During using it, wear suitable protective clothing.

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 41500ug/kg (41.5mg/kg)   National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse LD50 intravenous 50mg/kg (50mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 759, 1980.
rabbit LDLo intravenous 5385ug/kg (5.385mg/kg)   Journal of Bacteriology. Vol. 32, Pg. 227, 1936.

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