|Synonyms:||Con A;Concanavaline A;Lectins, concanavalins A;|
|Solubility:||PBS: 5 mg/mL, slightly hazy|
|Transport Information::||UN 1170 3/PG 3|
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The CAS registry number of Concanavalin A is 11028-71-0. It is a lectin (carbohydrate-binding protein) originally extracted from the jack-bean. And it is the first lectin to be available on a commercial basis. In addition, it is a plant mitogen, and is known for its ability to stimulate mouse T-cell subsets giving rise to four functionally distinct T cell populations.
Uses of Concanavalin A: it is widely used in biology and biochemistry to characterize glycoproteins and other sugar-containing entities on the surface of various cells. And it is used to purify glycosylated macromolecules in lectin affinity chromatography. Moreover, it is useful in applications requiring solid-phase immobilization of glycoenzymes.
When you are using this chemical, please be cautious about it as the following:
This chemical is flammable. During using it, wear suitable protective clothing.
The toxicity data is as follows:
|Organism||Test Type||Route||Reported Dose (Normalized Dose)||Effect||Source|
|mouse||LD50||intraperitoneal||41500ug/kg (41.5mg/kg)||National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,|
|mouse||LD50||intravenous||50mg/kg (50mg/kg)||Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 759, 1980.|
|rabbit||LDLo||intravenous||5385ug/kg (5.385mg/kg)||Journal of Bacteriology. Vol. 32, Pg. 227, 1936.|