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Cyanoacetohydrazide

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Name

Cyanoacetohydrazide

EINECS 205-437-2
CAS No. 140-87-4 Density 1.223 g/cm3
PSA 78.91000 LogP -0.01882
Solubility almost transparency Melting Point 108-110 °C(lit.)
Formula C3H5N3O Boiling Point 405.605 °C at 760 mmHg
Molecular Weight 99.0922 Flash Point 199.103 °C
Transport Information UN 2811 Appearance Brown granular crystalline powder
Safety 26-28-36/37/39-45 Risk Codes 20/21/22-36/37/38
Molecular Structure Molecular Structure of 140-87-4 (Cyanoacetohydrazide) Hazard Symbols HarmfulXn
Synonyms

Aceticacid, cyano-, hydrazide (6CI,8CI,9CI);(Cyanoacetyl)hydrazine;(a-Cyanoacetyl)hydrazine;2-Cyanoacethydrazide;2-Cyanoacetohydrazide;2-Cyanoacetylhydrazide;AB-42;Armazal;Cianazil;Cyacetacid;Cyacetacide;Cyacetazid;Cyacetazide;Cyanacethydrazide;Cyanacetic acid hydrazide;Cyanacetohydrazide;Cyanacetylhydrazide;Cyanazide;Cyanizide;Cyanoacethydrazide;Cyanoacetic acidhydrazide;Cyanoacetic hydrazide;Cyanoacetohydrazide;Cyanoacetyl hydrazide;Cyanoethanoic hydrazide;Cyazid;Cyazide;Dictycide;Dictyzide;Helmox;Hidacian;Hidaciann;Leandin;Mackreazid;Malonitrile hydrazide;Malononitrilehydrazide;NSC 24261;Neohydrazid;Reacid;Reazid;Reazide;Tsiazid;a-Cyanoacetohydrazide;

Article Data 31

Cyanoacetohydrazide Chemical Properties

Empirical Formula: C3H5N3O
Molecular Weight: 99.0913 
Index of Refraction: 1.479
Density: 1.222 g/cm3
Flash Point: 199.1 °C
Enthalpy of Vaporization: 65.72 kJ/mol
Boiling Point: 405.6 °C at 760 mmHg
Vapour Pressure: 8.66E-07 mmHg at 25 °C
Melting point: 108-110 °C(lit.)
Appearance: Brown granular crystalline powder
Product categories of Cyanoacetic acid hydrazide (CAS NO.140-87-4): Small molecule;Aliphatics
Structure of Cyanoacetic acid hydrazide (CAS NO.140-87-4):
                             

Cyanoacetohydrazide Toxicity Data With Reference

1.    

orl-mus LD50:250 mg/kg

    CLDND*    Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ontario, Canada) AD277-689 .
2.    

scu-mus LD50:228 mg/kg ABMGAJ 21,635,68

Carcinogenicity of Cyanoacetic acid hydrazide (CAS NO.140-87-4) hasn't been listed as a carcinogen by NTP, IARC,ACGIH, or CA Prop 65. You can see actual entry in RTECS for complete information.

Cyanoacetohydrazide Consensus Reports

Cyanide and its compounds are on the Community Right-To-Know List.

Cyanoacetohydrazide Safety Profile

Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx and CN. See also NITRILES.
 

Hazard Codes: HarmfulXnIrritantXi
Risk Statements: 20/21/22-36/37/38
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-28-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S28:After contact with skin, wash immediately with plenty of soap-suds. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

Cyanoacetohydrazide Specification

 Cyanoacetic acid hydrazide ,its cas register number is 140-87-4. It also can be called Cyacetacide ; Acetic acid, 2-cyano-, hydrazide ; a-Cyanoacetohydrazide and Cyanoacetohydrazide . Cyanoacetic acid hydrazide (CAS NO.140-87-4) is a 21 carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands. Corticosterone is converted to aldosterone by aldosterone synthase, found only in the mitochondria of glomerulosa cells. It has only weak glucocorticoid and mineralocorticoid potencies in humans and is important mainly as an intermediate in the steroidogenic pathway from pregnenolone to aldosterone.

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